Francis Desharnais officially entered the world of comics in 2008 with the publication of Burquette (Les 400 coups). Since then, one project has followed another - sometimes writer, sometimes illustrator, sometimes both at the same time. Most of his comics are published by Pow Pow, notably La guerre des arts and La petite Russie. The latter won numerous awards (Prix des libraires, Prix ACBD, Une ville un livre). He also wrote Les premiers aviateurs and La conquête du cosmos (BDGest'art Award for Best American Comics), with Alexandre Fontaine Rousseau on the script. In 2023, he published his first two children's books: Claude Gauvreau : l’art vraiment bizarre expliqué aux enfants, and 5 dodos pour tout savoir sur les dragons.